Introduction To Clinical Pharmacology 8th Edition By Marilyn Winterton Edmunds – Test Bank

Chapter 11: Antineoplastic Medications
Edmunds: Introduction to Clinical Pharmacology, 8th Edition

MULTIPLE CHOICE

1. Which term refers to a medication that interferes with metabolic functions in cells?
a. Antibiotic
b. Alkylating agent
c. Antimetabolite
d. Mitotic inhibitor

ANS: C
Antimetabolites disrupt normal cell function by interfering with various metabolic func-tions of the cells.

DIF: Cognitive Level: Remember REF: p. 191 OBJ: 1
TOP: Antimetabolites KEY: Nursing Process Step: N/A
MSC: NCLEX: N/A

2. In observing a chemotherapy patient, an LPN/LVN must be aware of adverse effects from other products. The patient tells the nurse that he has found an herbal prep-aration to help control his nausea. Which represents the nurse’s best response?
a. “That sounds wonderful, and it’s inexpensive.”
b. “Stop taking this product; it is toxic.”
c. “Tell me the name of the herbal preparation you are taking.”
d. “Follow the instructions on how to take that preparation.”

ANS: C
Some herbal preparations may be helpful in dealing with nausea and vomiting due to chemotherapy. The nurse should find out what herbal preparation the patient is taking to ensure it does not react negatively with the other medications the patient is prescribed.

DIF: Cognitive Level: Apply REF: p. 192 OBJ: 2
TOP: Drug Interactions KEY: Nursing Process Step: Assessment
MSC: NCLEX: Physiological Integrity: Reduction of Risk Potential

3. What is the effect of chemotherapeutic agents on cells?
a. Slows cell growth
b. Kills malignant cells
c. Breaks down the bacterial cell wall
d. Increase helper T-cell production

ANS: A
Chemotherapeutic agents slow cell growth or delay the spread of malignant cells into other parts of the body.

DIF: Cognitive Level: Remember REF: p. 190 OBJ: 1
TOP: Chemotherapeutic Agents KEY: Nursing Process Step: N/A
MSC: NCLEX: N/A

4. Which common adverse reaction is associated with antineoplastic drugs?
a. Alopecia and bone marrow depression
b. Bone marrow stimulation and nausea
c. Diarrhea and blurred vision
d. Anorexia and rhinorrhea

ANS: A
The action of antineoplastic agents on normal cells causes many adverse reactions, which include alopecia and bone marrow depression.

DIF: Cognitive Level: Understand REF: p. 190 OBJ: 2
TOP: Antineoplastics KEY: Nursing Process Step: Assessment
MSC: NCLEX: Physiological Integrity

5. The nurse may include which diagnosis for a patient taking an antineo-plastic medication?
a. Decreased cardiac output
b. Deficient fluid volume
c. Social isolation
d. Imbalanced nutrition: more than body requirements

ANS: B
Nausea, vomiting, anorexia, and diarrhea are seen with almost all of the antineoplastic agents.

DIF: Cognitive Level: Apply REF: p. 192 OBJ: 2
TOP: Adverse Reactions KEY: Nursing Process Step: Diagnosis
MSC: NCLEX: Physiological Integrity: Reduction of Risk Potential

6. For which condition should the nurse take special care in an older patient who is receiving chemotherapy?
a. Anorexia and diarrhea
b. Dry eyes
c. Edema in the joints
d. Pain at injection site

ANS: A
The nurse must take special care to hydrate the patient because nausea, anorexia, and diarrhea all work to dehydrate patients who are undergoing chemotherapy.

DIF: Cognitive Level: Apply REF: p. 191 OBJ: 2
TOP: Geriatric Considerations with Chemotherapy
KEY: Nursing Process Step: Assessment MSC: NCLEX: Physiological Integrity

7. Which person is qualified to prepare and administer antineoplastic drugs?
a. Any trained drug representative
b. Any medical assistant
c. An advanced practice nurse
d. An oncology nurse

ANS: D
Some preparations should be given only by a physician or other health care provider such as a specially trained chemotherapy nurse.

DIF: Cognitive Level: Understand REF: p. 193 OBJ: 1
TOP: Antineoplastics KEY: Nursing Process Step: Implementation
MSC: NCLEX: Physiological Integrity

8. Which precautions should nurses administering antineoplastic preparations use?
a. Standard precautions as always
b. Proper hand hygiene after use
c. Preparation of medication in special areas
d. Preparation in direct light under a hood

ANS: C
Administration of these toxic products may pose a safety hazard to the nurse and patient. There should be a special area designated for mixing these preparations.

DIF: Cognitive Level: Apply REF: p. 193 OBJ: 1
TOP: Antineoplastics KEY: Nursing Process Step: Implementation
MSC: NCLEX: Physiological Integrity

9. For which organ may a patient with cancer be prescribed hormones?
a. Bone
b. Prostate
c. Brain
d. Liver

ANS: B
Some tumors, such as cancer of the prostate, may depend on male or female hormones, the chemicals produced by the sex glands.

DIF: Cognitive Level: Understand REF: p. 192 OBJ: 1
TOP: Hormones KEY: Nursing Process Step: N/A MSC: NCLEX: N/A

10. A patient taking Mustargen is suffering from alopecia. The nurse should in-clude which intervention in the care plan?
a. Provide ice chips.
b. Maintain IV hydration.
c. Use emollients on the affected area.
d. Offer the use of a scarf.

ANS: D
Hair loss secondary to chemotherapy is usually of great concern to the patient.

DIF: Cognitive Level: Apply REF: p. 195 OBJ: 2
TOP: Adverse Reactions KEY: Nursing Process Step: Planning
MSC: NCLEX: Physiological Integrity: Basic Care and Comfort